Resveratrol

According to available evidence, the ability of a substance to pass through the blood-brain barrier is significant as it could potentially aid in the control of brain inflammation. This is particularly crucial in the progression of various neurodegenerative disorders.
A recent report from Georgetown University Medical Center revealed that administering a certain treatment to individuals with Alzheimer's disease has proven to be beneficial. The treatment aids in restoring the integrity of the blood-brain barrier, a crucial protective barrier in the brain, and also reduces the ability of harmful immune molecules to enter the brain tissue. This discovery is significant as it suggests that the treatment may help slow down the inflammation and cognitive decline experienced by patients with Alzheimer's. When compared to a placebo, individuals receiving the treatment exhibited a noticeable decrease in the rate of inflammation and cognitive decline. This research offers promising insights into potential therapeutic approaches for Alzheimer's disease.

Physical and chemical properties

1. Extend life
By inhibiting PDE-4, activating AMPK, and then stimulating the functional activity of SIRT1, it achieves the effect of prolonging lifespan.
2. Improve metabolism
On the other hand, it can combine with LaminA in the human body to reduce the activity of LaminA, and then stimulate the functional activity of SIRT1 to achieve the effect of reviving AMPK and increasing the number of stem cells, thereby intervening and delaying the aging process, regulating body metabolism, and avoiding suffering from third-level metabolism. disease.
3. Anti-aging
SIRT1 must bind to NAD+ in the body to delay aging. It can also increase NAD+ in astrocytes by 5 times by activating NMNAT1, improve the efficiency of SIRT1, and then delay human aging.

Resource Plant

Polygonum is a perennial shrub-like herb, mainly distributed in Jiangnan provinces, Hubei, Sichuan and other places in China. Its roots and rhizomes are the main components. Naturally, it mainly exists in the form of knotweed, and the content of plants is very small. This method can obtain high levels of ingredients. Among them, the content of fresh roots of Polygonum cuspidatum is higher than that of fresh stems, and the fresh leaves hardly contain this component.

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